Prednisolone 5mg Tablets - 10’S

Prednisolone 5mg Tablets are a potent, prescription-only synthetic Glucocorticoid (corticosteroid). This medication is prescribed for its powerful anti-inflammatory and immunosuppressant actions, targeting the root causes of inflammation and overactive immune responses in various diseases.

Key Ingredient and Strength

The active compound is Prednisolone at a strength of 5 mg per tablet.

Main Uses (Indications)

• Treatment of severe and persistent asthma and severe allergic reactions.
• Management of autoimmune diseases, such as Rheumatoid Arthritis, Systemic Lupus Erythematosus (Lupus), and inflammatory bowel diseases.
• Short-term treatment of various inflammatory conditions of the skin, eyes, and lungs.

Usage Instructions (Itemized with Dosage/Duration)

1. Dosage: Dosage is highly variable and must be determined strictly by a physician, ranging from low maintenance doses to high-dose burst therapy.
2. Timing: The tablets are usually taken once daily in the morning, often with food or milk to minimize gastric irritation.
3. Tapering: It is crucial that treatment, especially after prolonged use, is gradually tapered (reduced slowly) under medical supervision, never stopped abruptly.

Potential Risks and Adverse Events

Side effects depend heavily on the dose and duration of use. Short-term use may cause insomnia, increased appetite, and mood swings. Long-term use risks include increased susceptibility to infection, Cushingoid appearance (face swelling), bone thinning (osteoporosis), and diabetes.

Warnings/Precautions

• Abrupt Cessation: NEVER stop taking Prednisolone suddenly, as this can lead to adrenal insufficiency (adrenal crisis), which is life-threatening.
• Infections: May mask signs of infection; report any fever or signs of illness immediately.
• Pre-existing Conditions: Use with extreme caution and regular monitoring in patients with diabetes, high blood pressure, or a history of stomach ulcers.

Quick Product Facts Table

Product Type	Prescription Drug (Corticosteroid)
Active Ingredient	Prednisolone
Strength	5 mg
Primary Focus	Anti-inflammatory, Immunosuppression
Daily Dosage (Example)	Highly individualized; once daily.
Warnings	Must be tapered; not for abrupt discontinuation.

Note:

Prednisolone 5mg is available as, Prednilone tablets, P-Solone 5mg, and Prednisolone Dawa. Always Present your prescription at the pharmacy to get the right item.

Mechanism of Operation

Prednisolone exerts its action by penetrating the cell membrane and binding to intracellular glucocorticoid receptors. The resulting complex translocates to the cell nucleus, where it modulates gene expression. Specifically, it suppresses the transcription of pro-inflammatory genes (like COX-2 and cytokines) and increases the transcription of anti-inflammatory proteins, resulting in a profound and broad reduction of inflammation and immune activity across multiple body systems.