Clarie OD 500mg ER Tablets contain clarithromycin in an extended-release form, designed for once-daily dosing. It is used for bacterial respiratory tract infections and certain skin infections in Tanzania.
Available Product Formulations
Extended-release tablet: clarithromycin 500 mg.
Uses
Community-acquired pneumonia, bronchitis, sinusitis, and some skin/soft tissue infections caused by susceptible organisms.
How to Use
- Dosage: Adults: usually 500 mg once daily, may be increased to 1000 mg once daily in severe infections.
- Duration: Typically 7–14 days depending on infection type and severity.
Side Effects
Nausea, diarrhea, abdominal pain, altered taste, headache. Rare: QT prolongation, liver dysfunction, hearing changes.
Interactions
Strong CYP3A4 inhibitor—may interact with statins, anticoagulants, digoxin, and other drugs. Avoid use with ergot derivatives and certain antiarrhythmics.
Warnings
Not for viral infections. Use with caution in liver or kidney impairment. Avoid in patients with known QT prolongation or arrhythmias.
Summary of Important Information
| Active Ingredients |
Clarithromycin 500 mg ER |
| Dosage Frequency |
Once daily |
| Starting Time |
Begin after prescription |
| Duration of Use |
7–14 days |
| Common Side Effects |
Nausea, diarrhea, altered taste |
| Warnings |
QT prolongation; CYP3A4 drug interactions; liver caution |
How Clarie OD 500mg ER Tablets Works
Clarithromycin binds to the 50S ribosomal subunit, blocking bacterial protein synthesis and halting bacterial growth.
