Details
Amlosun 5 mg Tablets contain amlodipine besilate equivalent to 5 mg amlodipine. It is a prescription medicine used to treat hypertension and angina by relaxing blood vessels, reducing resistance to blood flow, and lowering blood pressure. It belongs to the calcium channel blocker class.
Forms / Strengths
- 5 mg tablet (standard dose)
Main Indications
- Hypertension (high blood pressure)
- Chronic stable angina pectoris
- Vasospastic angina (Prinzmetal)
Usage Instructions (Adults)
- Take 5 mg once daily, at the same time each day for consistent levels.
- May be taken with or without food.
- If required, dose may be increased to 10 mg once daily under medical supervision.
- For patients with liver impairment, elderly, or sensitive patients, lower starting dose or slower titration may be advised.
Side Effects
- Swelling of ankles or feet (peripheral edema)
- Headache, dizziness, flushing
- Fatigue, nausea, somnolence
Interactions / Compatibility
- Avoid or monitor use with other blood-pressure lowering agents (risk of hypotension)
- Grapefruit juice may increase blood levels of amlodipine and raise side-effect risk
- Use caution in hepatic impairment.
Warnings / Precautions
- Not intended for acute angina relief (short-acting symptoms)
- Abrupt withdrawal is not recommended; must follow medical advice for discontinuation.
- Monitor for signs of low blood pressure, especially on standing (orthostatic hypotension).
- Consult health professional if pregnant or breastfeeding.
Quick Product Facts Table
| Feature |
Details |
| Drug Class |
Calcium Channel Blocker (Dihydropyridine class) |
| Strength |
5 mg per tablet |
| Typical Route |
Oral, once daily |
| Onset / Duration |
Onset within hours; effect lasts ~24 hours |
| Storage |
Store at room temperature, protect from light, moisture |
| Main Side Effects |
Peripheral edema, headache, dizziness, flushing |
| Serious Warnings |
Severe hypotension, heart failure exacerbation, arrhythmias in predisposed, use in hepatic impairment cautiously |
Mechanism of Action
Amlodipine binds to L-type calcium channels in vascular smooth muscle, reducing calcium influx, relaxing blood vessel walls (arterioles) thereby reducing peripheral resistance, lowering blood pressure, and improving coronary blood flow. The reduced afterload leads to reduced workload on heart, alleviating symptoms of angina.
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