Details
Adsorbed Tetanus Toxoid (TT) is an inactivated vaccine used to prevent tetanus — a serious infection caused by Clostridium tetani. It stimulates the body’s immune system to produce protective antibodies that neutralize tetanus toxin.
Form/Strength
- 0.5mL injection, containing Tetanus Toxoid adsorbed on aluminium hydroxide or phosphate
- For intramuscular use only
Main Uses
- Active immunization against tetanus
- Part of routine EPI immunization (children, adults, and pregnant women)
- Post-exposure prophylaxis for contaminated wounds
Dosage & Administration
- Inject 0.5mL intramuscularly, usually in the upper arm (deltoid) or thigh (anterolateral side).
- For adults and children above 6 weeks old.
- Booster doses may be given every 10 years or after injury.
Side Effects
- Pain, redness, or swelling at injection site
- Mild fever, fatigue, or body ache
- Rarely allergic reaction (anaphylaxis)
Contraindications
- Hypersensitivity to any vaccine component
- Severe illness – defer vaccination until recovery
Storage & Stability
- Store between +2°C and +8°C
- Do not freeze – loss of potency may occur
Quick Facts Table
| Feature |
Details |
| Active Ingredient |
Tetanus Toxoid (inactivated toxin) |
| Dose Volume |
0.5mL per injection |
| Route |
Intramuscular (IM) |
| Storage |
+2°C to +8°C |
| Common Use |
Prevention of tetanus |
| Population |
Children, Adults, Pregnant Women |
Mechanism of Action
The vaccine introduces inactivated tetanus toxin, prompting the immune system to produce neutralizing antibodies. These antibodies remain in circulation, protecting the body if exposed to the real tetanus bacteria.
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