Acnotin 10mg Capsules – 30’s

Acnotin 10mg Capsules are an oral medication for the treatment of severe acne (acne vulgaris) that has not responded to other therapies. As a retinoid, it works systemically to target the root causes of acne, offering a lasting solution for individuals facing persistent and severe skin issues in Tanzania and beyond. This product is a prescription medication and should only be used under the supervision of a healthcare professional.

Available Product Formulations

Acnotin is available in oral capsule form in two strengths: 10mg and 20mg. The dosage will be determined by your doctor based on the severity of your condition and your body weight.

Uses

Acnotin is used for the treatment of severe, disfiguring nodular acne that has failed to respond to conventional treatments, including topical therapies and oral antibiotics. It is also used to treat acne conglobata and acne that has a high risk of permanent scarring.

How to Use

• Dosage: The initial recommended dose is 0.5 mg per kg of body weight per day, which may be adjusted by your doctor based on your response. The capsules should be taken with food, once or twice daily.
• Duration: The typical course of treatment lasts for 16 to 24 weeks. A second course of treatment may be initiated after a period of at least eight weeks if needed.

Side Effects

Common side effects include dry skin, chapped lips, dry eyes, nosebleeds, and joint pain. More serious side effects can include mood changes, depression, and severe headaches. If you experience any of these side effects or any other unusual symptoms, you must consult your doctor immediately.

Interactions

Do not take Acnotin with tetracycline antibiotics, as this may increase the risk of a serious condition called pseudotumor cerebri (benign intracranial hypertension). It should not be used with other vitamin A supplements, as it can lead to vitamin A toxicity. Consult your doctor if you are taking any other medications.

Warnings

Acnotin is a teratogenic drug, which means it can cause severe birth defects. Female patients must be on a reliable form of contraception for at least one month before starting treatment, during treatment, and for one month after stopping treatment. Do not donate blood while on this medication and for one month after stopping. Avoid excessive sun exposure. Patients with diabetes or liver disease should use this medication with caution. This medication is not recommended for children under 12 years of age.

Summary of Important Information

How Acnotin 10mg Works

Acnotin’s active ingredient, isotretinoin, is a synthetic isomer of all-trans retinoic acid. Its primary mechanism of action in treating severe acne is its ability to reduce the size and activity of sebaceous glands. This leads to a significant decrease in sebum production, a key factor in the pathogenesis of acne vulgaris. It also has anti-inflammatory properties and helps to regulate cellular differentiation and proliferation, preventing hyperkeratinization within the hair follicles, which is another crucial step in the formation of acne lesions. This comprehensive action addresses the key etiologic factors of acne, leading to a long-term remission in many patients.